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院       系: 食品学院

办公电话:0411-86318657

电子信箱: wuxiaomeng0812@163.com

更新时间: 2024-08-01

吴晓萌

       副教授/硕导


个人简介

       2022.11月至今,大连工业大学 副教授;

       2020.12-2021.11,大连工业大学 讲师;

       2018.7-2020.12,大连工业大学 博士后研究人员;

       2015.9-2018.7,天津科技大学,食品科学,博士学位;

       2011.9-2014.7,辽宁医学院,食品科学,硕士学位;

       2007.9-2011.7,辽宁医学院,食品科学与工程,学士学位。


研究方向

       乳品科学与技术,包括(1)功能性乳蛋白、乳肽分离技术开发与应用;(2)靶向功能性益生菌筛选及应用。


主要成果

       主持/参与科研项目多项,其中,国家项目5项,发表学术论文25篇,其中以第一作者或通讯作者发表SCI/EI收录论文25余篇;参与制定团体标准1项;获辽宁省教学创新大赛二等奖1项。


科研项目

       主持科研项目8项,其中国家级项目2项。主持的科研项目如下:

       1. 国家自然基金面上项目 (32372342), “牛乳β、κ-酪蛋白肽通过肠道菌群提高机体免疫作用分子机制研究”2024. 1~2027. 12,50万元,在研,主持;

       2. 国家重点研发计划项目子课题 (2022YFD2101503), “基于暴露动物的免疫与消化功效评价模型建立及特征功能组分互作功效研究”2022. 11~2027,150万元,在研,主持;

       3. 辽宁省教育厅项目面上项目 (LJKMZ20220897),“牛乳β+κ-酪蛋白 免疫调节肽结构特征及形成机制研究”, 2022. 09~2024. 09, 3万元,在研,主持;

       4. 博士后面上基金一等资助“调控胶原-酪蛋白体系自聚的关键因素及动力学机制研究”(2019M660062),主持在研;12万,结题,主持。

       5. 企业横向,海参压片糖果(纯粉型)产品抗氧化性、免疫功能及抗结肠癌作用效果评价, 5万元,结题,主持;

       6. 企业横向,泡椒及青辣椒酱发酵优势菌种的筛选及其功能性评价, 5万元, 结题,主持;

       7. 企业横向,益生菌免疫调节及缓解衰老认知损伤功能评价, 15万元,在研,主持;

       8. 企业横向,酪蛋白免疫调节肽制备技术,10万元,在研,主持。


出版著作和论文

主要代表论文:

       1. Hui Nie; Xinxin Wang; Yanghe Luo; Fanhua Kong; Guangqing Mu;Xiaomeng Wu*. Mechanism Explanation on Improved Cognitive Ability of D-gal inducing Aged Mice Model by Lactiplantibacillus plantarum MWFLp-182 via Microbiota−Gut−Brain Axis, Journal of Agricultural and Food Chemistry, 2024, doi: org/10.1021/acs.jafc.3c09675

       2. Xiaomei Zhang; Xinxin Wang; Jinlian Li; Guangqing Mu ;Xiaomeng Wu*. Study on a galactose decomposition strain of Lactiplantibacillus plantarum MWLp-4 from human milk: Safety evaluating and key genes analysis of potential probiotic function, Food Bioscience, 2023, 54, 102934.

       3. Hui Nie; Xutong Ma; Fanyu Kong; Yanghe Luo; Guangqing Mu*;Xiaomeng Wu*. Improvement of Lactiplantibacillus plantarum MWFLp-182 on Oxidative Deficits induced by in 2,2'-Azobis (2-methylpropionamidine) Dihydrochloride and the Relating Key Gene Analysis. Food Science and Human Wellness, 2023, 9250026.

       4. Chenhui Lei ,Xiaomeng Wu*., Shengyuan Wang, Ang Gao, Guangqing Mu, Fang Qian; Mechanism analysis of promoting calcium absorption and bone formation of peptides from different casein fractions, Food Bioscience, 2024, 58,  103728

       5. Xiao mei Zhang; Junhao Jin; Jinghong Zhao; Hui Nie; Guangqing Mu;Xiaomeng Wu*. Study on a galactose decomposition strain of Lactiplantibacillus plantarum MWLp-4 from human milk: Safety evaluating and key genes analysis of potential probiotic function, Food Bioscience, 2023, 54, 102934.

       6. Qing Zhao; Zining Wang; Zengxin Yu; Zhongyang Gao; Guangqing Mu*;Xiaomeng Wu*. Influence on physical properties and digestive characters of fermented coconut milk with different loading proportion of skimmed coconut drink using Lactiplantibacillus plantarum MWLp-4 from human milk mixing with Commercial bacteria, Food Bioscience, 2023, 53, 102598.

       7. Yajuan Wang; Haoyu Yang; Guangqing Mu*;Xiaomeng Wu*. Safety evaluation and complete genome analysis emphasis on extracellular polysaccharide of two strains of Limosilactobacillus fermentum MWLf-4 and Lactipiantibacillus plantarum MWLp-12 from human milk. Food Bioscience, 2023, 51, 102356.

       8. Hui Nie; Zhongyang Gao; Yajuan Wang; Feiyang Wu; Guangqing Mu*;Xiaomeng Wu*. Influence of soaking Malus domeri (Bois) Chev. leaves on gut microbiota and metabolites of long-living elderly individuals in Hezhou city, Guangxi, China. Food Science and Human Wellness, 2023, 06.

       9. Junpeng Zhang#;Xiaomeng Wu#; Jinghong Zhao; Xutong Ma; Safian Murad M; Guangqing Mu*. Effects of different casein fractions on immune regulation via peptidome comparison and mice induced by cyclophosphamide, Journal of Dairy Science, 2023, 107:40-61

       10. Yajun Wang; Kaibo Feng; Junhao Jin; Safian Murad M.; Guangqing Mu*;Xiaomeng Wu*. Comparison on properties between normal and A2 bovine milk fermented using commercial bacteria mixed with/without two probiotics from human milk. International Journal of Biological Macromolecules, 2022, 216:105-113.


在读学生人数

       指导/协助指导硕士研究生6名,协助指导博士研究生3名。


毕业学生人数

       已毕业硕士研究生1人;协助指导硕士研究生3人,均已攻读博士学位。