张雪迪

       讲师

个人简介

       2022.08-至今，大连工业大学食品学院，讲师；

       2018.09-2022.07，大连工业大学，食品科学与工程，博士；

       2015.09-2018.07，大连海洋大学，水产品加工及贮藏工程，硕士；

       2011.09-2015.07，内蒙古大学，食品科学与工程，学士。

研究方向

       海洋类营养功能因子稳态化载运体系构建及营养精准干预机制研究

科研项目

       （1） 中国农村技术开发中心, 国家重点研发计划子课题, 2023YFD2100605, 褐藻营养食品功效增强技术研究, 2023-12 至 2026-11, 60万元, 在研, 主持。

       （2） 辽宁省教育厅, 青年项目, JYTQN2023119, 二十二碳六烯酸-虾青素酯型乳剂对肠道炎性内环境的调控研究, 2023-09 至 2025-09, 3万元, 在研, 主持。

       （3）科研启动经费项目，724001010131，虾青素载运体系对热应激诱导下睾丸生精性能的调控机制，2024-06至2026-06，12万元，在研，主持。

出版著作和论文

专著情况：

       1. Mingqian Tan*,Xuedi Zhang, Shan Sun, Guoxin Cui, Nanostructured steady-state nanocarriers for nutrients preservation and delivery, Advances in Food and Nutrition Research, 2023.

主要代表论文：

       1.Xuedi Zhang, Xue Zhao, Shanshan Tie, Jiaxuan Li, Wentao Su, Mingqian Tan*. A smart cauliflower-like carrier for astaxanthin delivery to relieve colon inflammation. Journal of Controlled Release, 2022, 342: 372-387.

       2.Xuedi Zhang, Xue Zhao, Zheng Hua, Shanghua Xing, Jiaxuan Li, Siyuan Fei, Mingqian Tan*. ROS-triggered self-disintegrating and pH-responsive astaxanthin nanoparticles for regulating the intestinal barrier and colitis. Biomaterials, 2023, 292: 121937.

       3.Xuedi Zhang, Xue Zhao, Shanshan Tie, Haitao Wang, Mingqian Tan*. Ultrasonic Self-Emulsification Nanocarriers for Cellular Enhanced Astaxanthin Delivery. Journal of Agricultural and Food Chemistry, 2021, 69(9): 2719-2728.

       4.Xuedi Zhang, Jun Li, Jianing Niu, Xuanping Bao, Haidong Zhao, Mingqian Tan*. Fluorescent carbon dots derived from urine and their application for bio-imaging. Methods, 2019, 168, 84-93.

       5. Shanshan Tie,Xuedi Zhang, Haitao Wang, Yukun Song, Mingqian Tan*, Procyanidins-loaded complex coacervates for improved stability by self-crosslinking and calcium ions chelation, Journal of Agricultural and Food Chemistry, 2020, 68, 10, 3163-3170.

       6. Zheng Hua,Xuedi Zhang, Yannan Chen, Ronggang Liu, Yu Li, Jiaxuan Li, Donghong Liu, Mingqian Tan*, A bifunctional hepatocyte-mitochondrion targeting nanosystem for effective astaxanthin delivery to the liver. Food Chemistry, 2023, 424:136439.

       7. Xue Zhao,Xuedi Zhang, Shanshan Tie, Shuai Hou, Haitao Wang, Yukun Song, Rewa Rai and Mingqian Tan*, Facile synthesis of nano-nanocarriers from chitosan and pectin with improved stability and biocompatibility for anthocyanins delivery: An in vitro and in vivo study, Food Hydrocolloids, 2020, 109, 106114.

       8. Zheng Hua,Xuedi Zhang, Xue Zhao, Bei-Wei Zhu, Donghong Liu* and Mingqian Tan*, Hepatic-targeted delivery of astaxanthin for enhanced scavenging free radical scavenge and preventing mitochondrial depolarization, Food Chemistry, 2023, 406, 135036.

       9. Zheng Hua,Xuedi Zhang, Shanghua Xing, Jiaxuan Li, Duo Liang, Yannan Chen, A.M. Abd El-Aty, Bei-Wei Zhu, Donghong Liu* and Mingqian Tan*, Design and preparation of multifunctional astaxanthin nanoparticles with good acid stability and hepatocyte-targeting ability for alcoholic liver injury alleviation, Materials Today Nano, 2024, 25, 100436.

专利情况：

       （1）谭明乾，张雪迪，铁珊珊，李佳璇，崔国馨. 一种 TPP 线粒体靶向虾青素乳液及其制备方法，201910977742.2。

       （2）谭明乾，张雪迪，赵雪，铁珊珊，李佳璇，吕玥琪，袁龙. 一种刺激响应型虾青素纳米颗粒及其制备方法和在线粒体靶向、缓解结肠炎症方向的应用，202011390337.X。

       （3）谭明乾，张雪迪，于潇婷，陈衍男，柳康静，袁龙. 一种 ROS 刺激响应型虾青素纳米颗粒及其制备方法和应用，202110816654.1。